Ensuring Pharmaceutical Product Success through Excipient QbD Efforts
نویسندگان
چکیده
It isessential to understand excipients’ critical material attributes. A QbDstrategy that includes historical data analysis and experimental work has beenused in functional excipients such as Hypromellose (HPMC) develop thisunderstanding. The use of multivariate helped identify excipientvariability the support it could provide improve final product robustness.
منابع مشابه
Potential aspects of chitosan as pharmaceutical excipient.
Interest in use of the polysaccharide chitosan as a pharmaceutical excipient by different dose routes and for a number of applications is not new but it still does not appear to be present in any marketed drugs. Also a novel excipient in a new formulation requires a lot of safety consideration. Published literature showed that chitosan has low oral toxicity and prior human exposure has occurred...
متن کاملOkra Gum as a Pharmaceutical Excipient
The University Repository is a digital collection of the research output of the University, available on Open Access. Copyright and Moral Rights for the items on this site are retained by the individual author and/or other copyright owners. Users may access full items free of charge; copies of full text items generally can be reproduced, displayed or performed and given to third parties in any ...
متن کاملFeline Hyperthyroidism – Ensuring Treatment Success
Hyperthyroidism is a disease of older cats consequently many patients have concurrent diseases. Indeed therapy for hyperthyroidism is often associated with unmasking of concurrent chronic kidney disease. Selecting the appropriate therapy for hyperthyroid cats with concurrent conditions is challenging. Traditional management options for feline hyperthyroidism include thyroidectomy, anti-thyroid ...
متن کاملChitosan: a Novel Excipient in Pharmaceutical Formulation: a Review
Chitosan is a cationic natural polysaccharide which is derived from the chitin of crustaceans, with crabs and shrimp-shell wastes as its principal source. Its properties includes extent of deacetylation and the average molecular weight of polymer as well as low toxicity and good bioavailability make it a novel excipient in pharmaceutical formulation as a relatively new development. Together wit...
متن کاملModified Starch and Its Potentials as Excipient in Pharmaceutical Formulations
These are additives used to convert pharmacologically active compounds into pharmaceutical dosage forms suitable for administration to patients [1]. Although excipients are the non-active ingredients, they are essential in the successful production of acceptable solid dosage forms such as tablets and powders. For example, the lack of filling materials would make it exceedingly challenging, if n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British journal of pharmacy
سال: 2022
ISSN: ['2058-8356']
DOI: https://doi.org/10.5920/bjpharm.1243